منابع مشابه
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY Hyperhomocysteinemia in cerebral vein thrombosis
High plasma levels of total homocysteine (tHcy) are a risk factor for deep vein thrombosis. Because no information on the relationship between cerebral vein thrombosis and hyperhomocysteinemia is available, a case–control study of 121 patients with a first episode of cerebral vein thrombosis and 242 healthy control subjects was carried out. Fasting plasma levels of tHcy and their postmethionine...
متن کاملHyperhomocysteinemia presenting as superior mesenteric artery thrombosis.
We report a 23-year-old man who presented with acute abdomen. At laparotomy, he was diagnosed to have superior mesenteric artery thrombosis, with consequent extensive intestinal gangrene extending from the proximal jejunum till the mid transverse colon. He subsequently developed dry gangrene of the digits. Further evaluation showed that he had marked hyperhomocysteinemia. The gangrenous bowel w...
متن کاملHyperhomocysteinemia as a risk factor for deep-vein thrombosis.
BACKGROUND Previous studies have suggested that hyperhomocysteinemia may be a risk factor for venous thrombosis. To assess the risk of venous thrombosis associated with hyperhomocysteinemia, we studied plasma homocysteine levels in patients with a first episode of deep-vein thrombosis and in normal control subjects. METHODS We measured plasma homocysteine levels in 269 patients with a first, ...
متن کاملHyperhomocysteinemia, low folate and vitamin B12 concentrations, and methylene tetrahydrofolate reductase mutation in cerebral venous thrombosis.
BACKGROUND AND PURPOSE Elevated plasma levels of homocysteine are associated with an increased risk of deep-vein thrombosis. Through a case-control study, we examined the potential association among homocysteine, folate and vitamin B12 levels, and the common C677-->T mutation in the methylene tetrahydrofolate reductase (MTHFR) gene in patients with cerebral venous thrombosis (CVT). METHODS Fo...
متن کاملHEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY Effect of hyperhomocysteinemia on protein C activation and activity
Hyperhomocysteinemia has been proposed to inhibit the protein C anticoagulant system through 2 mechanisms: decreased generation of activated protein C (APC) by thrombin, and resistance to APC caused by decreased inactivation of factor Va (FVa). We tested the hypotheses that generation of APC by thrombin is impaired in hyperhomocysteinemia in monkeys and that hyperhomocysteinemia produces resist...
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ژورنال
عنوان ژورنال: Clinical & Laboratory Haematology
سال: 2000
ISSN: 0141-9854
DOI: 10.1046/j.1365-2257.2000.00301.x